Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s. It has been used for pediatric cardiac surgery in Boston’s Children Hospital since 1994 and, since 2003, it has been successfully used for adult cardiac surgery as well [8].

A novel formula for inducing cardioplegia was introduced in congenital heart surgery in 1995.5,6 Led by Pedro del Nido, MD, researchers from the University of Pittsburgh patented this formula as a single dose of a modiﬁed depolarizing solution. Commonly referred to as ‘‘del Nido solution,’’ this blood and crystalloid

However, its use in the field of adult cardiac surgery is not popular yet. We evaluated efficacy of DN cardioplegia in adult cardiac surgical patients.Fifty-three Asanguinous, Del Nido cardioplegia was used for myocardial protection. Warm induction followed by cold infusion prevented any agglutination and eliminated the need for subsequent cardioplegia doses. Following the cross-clamp period, the heart returned to normal sinus rhythm without need for defibrillation. Composition of del Nido and Blood Cardioplegia Solutions. Del Nido solution is composed of mixed blood and Plasma-Lyte A (1:4) (total volume: 1060 mL). Mannitol (3.26 g), potassium chloride (K, 26 mEq), magnesium sulphate (Mg, 2 g), lidocaine (130 mg), and sodium bicarbonate (13 mEq) were added to the del Nido solution.

Cardioplegia del nido

Del Nido (DN) cardioplegia was formulated to act as single-dose administration in pediatric patients. Com-pared to the traditional 4:1 blood cardioplegia, DN is more dilute (1:4, blood:crystalloid), has lower Ca+2, and * Correspondence: ig2006@cumc.columbia.edu Department of Surgery, Division of Cardiothoracic Surgery, College of We conducted a prospective randomized trial to compare del Nido (DN) cardioplegia with conventional cold blood cardioplegia (St Thomas [STH]) in pediatric patients. We randomized 100 pediatric patients aged ≤12 years undergoing elective repair of ventricular septal defects and tetralogy of Fallot to the DN and the STH groups. In the DN group, a 20 mL/kg single dose was administered. In the 16 Nov 2020 References (52) [4] Del Nido is a crystalloid-based cardioplegia known to have a prolonged arrest time due to the lignocaine and magnesium 14 Jul 2020 The del Nido cardioplegia solution (DNS) was first formulated for pediatric cardiac surgery in the early 1990s and has been widely used ever 18 Sep 2019 Del Nido cardioplegia was initially used in pediatric patients and has been expanding into adult cardiac centers over the last decade.

We evaluated efficacy of DN cardioplegia in adult cardiac surgical patients.Fifty-three Asanguinous, Del Nido cardioplegia was used for myocardial protection.

The evolution of myocardial protection techniques has been both the source of milestone advancements and controversial debate in cardiac surgery. Our institution has modified a low-prime cardioplegia system (CPS) and adopted a single-dose cardioplegia solution (del Nido cardioplegia) for our congenital heart disease population. The goal of this article is to describe our CPS and outline our

This is the first Argentine report of Del Nido cardioplegia Background: del Nido cardioplegia is an extracellular, single-dose, non-calcium cardioplegic solution that has been increas- ing in popularity for the last decade. 11 Dec 2019 Dr. Pedro del Nido (dN) developed a cardioplegic solution, especially for the myocardial protection in neonatal and pediatric cardiac surgery 4 Feb 2020 Our study concludes that Del-Nido cardioplegia provide better myocardial protection and less cross clamp and bypass time. Cardiac enzymes, 26 Jan 2020 operation with either conventional cold blood cardioplegia with St Thomas 2 solution (STH), or del Nido cardioplegia.

Objective: The del Nido cardioplegia solution provides a long period of arrest with single dose as compare to St. Thomas cardioplegia solution. In our study we compared outcomes of del Nido and St. Thomas cardioplegia in adult open cardiac surgeries. Methods: Sixty patients were studied between January 2017 to December 2017. Out of which 30 patients were operated on St. Thomas cardioplegia …

Different cardioplegic strategies have been evaluated. Del Nido cardioplegia was initially used in pediatric patients and has been expanding into adult cardiac centers over the last decade. Del Nido cardioplegia is routinely used in clinical practice both in paediatric and adult population in high volume centres. It could be a safe, effective and cheap myocardial protection strategy of universal implementation in cardiac surgery. Additional prospective studies are needed to confirm these data. The del Nido cardioplegia is a crystalloid solution (Plasma-Lyte A, lidocaine, magnesium sulfate, potassium chloride, mannitol, sodium bicarbonate), mixed with blood in a 1:4 ratio (blood/crystalloid). Lidocaine is believed to be the primary component, as it increases the myocyte refractory period and reduces sodium and calcium influx.

Cardioplegia is an important strategy for myocardial protection during cardiac surgery. This meta-analysis was to compare the effects of del Nido and conventional cardioplegia in adult patients. From November 2016 to October 2017, Del Nido cardioplegia was used in 131 consecutive patients (DN group) and compared using a propensity score to 251 patients who had received intermittent cold blood cardioplegia (CB group) and operated during the immediate period prior. All patients were operated by one surgeon (FJ). del Nido (DN) cardioplegia was initially developed to protectpaediatric myocardium and has customarily been used in congenital heart operations [ 1 ].
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Del Nido cardioplegia is routinely used in clinical practice both in paediatric and adult population in high volume centres. It could be a safe, effective and cheap myocardial protection strategy of universal implementation in cardiac surgery. Additional prospective studies are needed to confirm these data. The del Nido cardioplegia is a crystalloid solution (Plasma-Lyte A, lidocaine, magnesium sulfate, potassium chloride, mannitol, sodium bicarbonate), mixed with blood in a 1:4 ratio (blood/crystalloid). Lidocaine is believed to be the primary component, as it increases the myocyte refractory period and reduces sodium and calcium influx.

2015-11-01 · Del Nido cardioplegia is routinely used in clinical practice both in paediatric and adult population in high volume centres. It could be a safe, effective and cheap myocardial protection strategy of universal implementation in cardiac surgery. Additional prospective studies are needed to confirm these data. Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s.
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It was subsequently tried in adult cardiac surgery, with good results.